As IFNγ is thought to be a principal driver of LRRK2 expression in myeloid cells [37], higher IFNγ levels that develop in female mice may explain higher extracellular LRRK2 levels, though larger group sizes may be needed for definitive correlations due to the variable responses to sepsis in these outbred mice. This evidence concerns the gene LRRK2 and Sepsis.