<h4>Purpose</h4>The purpose of the study was to evaluate the expression and function of basic leucine zipper ATF-like transcription factor (BATF) in colorectal cancer (CRC), and its correlation with 2-deoxy-2[<sup>18</sup>F]fluoro-D-glucose (<sup>18</sup>F-FDG) positron emission tomography/computed tomography (PET/CT) parameters.<h4>Methods</h4>The TIMER database, GEPIA database, TCGA, and GEO database were used to analyze the expression profile of BATF in human cancers. Here, BATF is linked to colorectal carcinoma.