We identified YWHAE as significantly associated with liver fibrosis, AVIL, FIS1, MUC1, ACOT7, CLUH, HNF4A, and TNFSF10 with liver cancer, and AVIL with liver disease-related mortality (FDR-adjusted P values < 0.05). The gene discussed is HNF4A; the disease is Hepatic fibrosis.