RUNX1 and myocardial infarction: Recent studies using experimental MI models showed that tamoxifen-induced Runx1-deficiency preserves myocardial contractility after MI (McCarroll et al. 2018) and inhibiting RUNX1 in the BZ via short-hairpin RNA interference or small molecule Ro5-3335 prevents contractile dysfunction following MI (Martin et al. 2023).