Furthermore, we confirmed a closely positive correlation among MYC, ZNF706, and SLC7A11 with each other in the mRNA and protein levels, indicating ZNF706 might be a critical hub to functionally link MYC to the maintenance of redox homeostasis in tumor cells by regulating SLC7A11 and consequently promotes advanced progression in HCC (Fig. 9H). Here, MYC is linked to neoplasm.