SLC7A11 and hepatocellular carcinoma: Furthermore, we confirmed a closely positive correlation among MYC, ZNF706, and SLC7A11 with each other in the mRNA and protein levels, indicating ZNF706 might be a critical hub to functionally link MYC to the maintenance of redox homeostasis in tumor cells by regulating SLC7A11 and consequently promotes advanced progression in HCC (Fig. 9H).