CD8A and neoplasm: Interestingly, the mice that were infected with the wild-type LCMV (which showed robust P14 expansion) exhibited superior tumor control relative to the mice that were infected with the LCMV ΔGP33 variant (Figure 3K), suggesting that “bystander” activation of virus-specific CD8+ T cells can facilitate tumor control in a host devoid of tumor-specific T cell responses.