HLA-C and neoplasm: Intratumoral r3LCMV therapy also induced potent antitumoral effects in other tumor models, such as the MC38 colon adenocarcinoma (Figure 2, E and F), and in mice with different genetic backgrounds (Figure 2, G and H), suggesting a generalizable antitumor effect independent of the major histocompatibility complex (MHC) haplotype.