IL13RA2 and central nervous system cancer: Interleukin 13 receptoralpha 2 (IL-13Rα2) has been extensivelyinvestigated in GBM and is reported to be overexpressed in three outof four glioma patients.64 Additionally,the absence of IL13Rα2 in the normal tissues surrounding GBMenhances its suitability as a target.