In vivo results showed that TR-liposomes could better target GBM cells anderadicate GSCs, demonstrating increased median survival time in glioma-bearingmice.131 In addition, the c(RGDfK) peptidewas combined with peptide-22, a specific ligand for LDLR, and attachedto DOX-loaded liposomes. The gene discussed is LDLR; the disease is glioblastoma.