ELISA conducted on serum collected 10 days postinfection from both saline and RRV-infected WT-BALB/c and TLR3 KO mice revealed that WT-BALB/c mice expressed significantly higher levels of CXCL9 and CXCL10 after RRV infection while TLR3 KO mice show no significant increase in CXCL9 or CXCL10 following infection (Fig. 9, A and B). This evidence concerns the gene CXCL10 and infection.