Among 69 significant loci identified by cross-trait meta-analysis using MTAG, we highlighted 4 overlapped loci among 10 pairs of 5 kidney function biomarkers traits and 2 mental disorders, including the genes GCKR, MUC1, HSPA1A and KRT18P1. For GCKR, our analysis found it was shared by BIP with BUN, eGFRcrea, eGFRcys and urate, which was agreed by many previous studies. This evidence concerns the gene GCKR and mental disorder.