WDR72 and diabetes mellitus: In Africans, rs12906891 (R2 = 0.209 with rs72747347) and rs11070992 (R2 = 0.210 with rs72747347) variants in WDR72 have been associated with proliferative diabetic retinopathy (PDR), a sight-threatening complication of diabetes that is associated with longer duration of diabetes and poor glycemic control (P = 9.7E-10; OR:1.46 and P = 4.2E-08; OR:1.28, respectively) [140].