NOS3-rs7830 (R2 = 0.494 with rs891511) has been associated with the risk of DKD in T2DM patients of Greek Caucasian origin (OR: 1.598; CI95%: 1.152–2.217; 121 DKD/220 T2DM) [66]. This evidence concerns the gene NOS3 and type 2 diabetes mellitus.