Notably, the ubiquitome analysis of the Clinical Proteomic Tumor Analysis Consortium (CPTAC) lung squamous cell carcinoma (LUSC) dataset (Satpathy et al, 2021) revealed that lung tumor samples presented decreased levels of NRAS and KRAS ubiquitination at K128 in comparison to normal tissue (Fig. 4G). This evidence concerns the gene NRAS and squamous cell lung carcinoma.