C3 and Hepatic fibrosis: At baseline, mean alanine aminotransferase (ALT), aspartate aminotransferase (AST), fibrosis-4 (FIB-4) index, Enhanced Liver Fibrosis (ELF) score, cytokeratin-18 (K-18) and serum pro-peptide collagen III (pro-C3) were normal or modestly elevated (Table 2).