Rescue of microglia and microphage recruitment was observed when LOC-deficient cancer cells were supplemented with recombinant human MIF1 (rhMIF1), whereas co-treatment with an antibody to CD74, the receptor for MIF1, abrogated the rescue observed following MIF1 supplementation (Fig. 4c,d and Extended Data Fig. 2c,d). Here, HERPUD1 is linked to cancer.