LOXL1 and central nervous system cancer: Analysis of glioma-infiltrating microglia/macrophage (GIM) signatures30 for this subset of RNAs in bulk RNA-seq of samples from patients with primary glioblastoma (CGGA cohort) showed that the expression levels of four (LOC105375914, LOXL1–AS1, LOC100130476, LOC100130476 and OSMR–AS1) correlated positively with increased infiltrating microglia/macrophage signature, as indicated by the higher GIM score (Fig. 1c).