LRRK2 and Parkinson disease: This is evidenced first and foremost by the discovery of RAB32 p.S71R, but also by the recovery of known ultrarare PD variants that had not previously been detectable in genome-wide case–control analyses (LRRK2 p.R1441C, MAFctrl 0.000014, P = 2.27 × 10−10).