WASF3 and neoplasm: Assessment of cell invasion via Matrigel assays reproducibly demonstrated the statistically significant decrease in invasion relative to control for ASO-mediated LINC03045 KD only (54.8% decrease, p = 0.002), and when “rescuing” LINC03045 KD tumor cells with concurrent WASF3 overexpression, cells demonstrated a statistically significant increase in invasive capacity compared to LINC03045 KD only cells (234.5% increase, p = 0.002) (Fig 8B and 8C).