MAPT and Alzheimer disease: LASSO logistic regression analyses revealed that the optimal model for predicting all-cause dementia included a predictor for temporal meta-ROI tau (β, 0.89; SE, 0.28; P = .001), AD signature cortical thickness (β, 0.96; SE, 0.29; P = .001), and the MTA visual read (β, 0.71; SE, 0.30; P = .02).