High expression of YTHDF1 enhances the activation of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway, promoting proliferation, cell cycle progression, migration, invasion, and epithelial-mesenchymal transition of liver cancer cells [102]. This evidence concerns the gene MTOR and liver cancer.