DNM1 and infection: Phage defense systems were diverse across the cyanobacterial population in Lake O. Additionally, genes for phage defense systems with different mechanisms were present, including those involved in nucleic acid degradation, such as CRISPR, RMs, phage argonautes (pAgos), bacteriophage exclusion, and SspBCDE (48) and abortive infection and the like, such as AbiE, AbiU, and dynamins (Fig. 7) (48, 80).