We prepared an FcαRIR209L/FcRγ transfectant (I3D) from a mouse macrophage cell line (RAW264.7).<h4>Methods</h4>Anti-FcαRI or control antibody was used to investigate a high-fat-diet-induced FcαRIR209L/FcRγApoE<sup>-/-</sup> mouse model of atherosclerosis. This evidence concerns the gene FCER1G and atherosclerosis.