Viruses that infect the brain lead to encephalopathies and can have the potential to trigger neurodegeneration and the development of PD through multiple pathways.98 COVID-19 infection can be considered as a potential “environmental factor” in triggering the development of PD in individuals carrying genetic susceptibility factors like the GBA and PRKN gene variants.109. The gene discussed is GBA1; the disease is Parkinson disease.