The aim of this study was to screen a multicentre early onset and familial PD cohort from 9 movement disorder centres across Central Europe within the Central European Group on Genetics of Movement Disorders (CEGEMOD) consortium [17] for rare LRRK2 variants using whole exome sequencing (WES) data to access the possible contribution of proposed p.L1795F LRRK2 variant to PD in Central Europe. This evidence concerns the gene LRRK2 and Parkinson disease.