To additionally control for potential effects of between-cohort differences in cognition, and inform generalizability of cutoffs between studies, we also selected BioFINDER-2 participants with MCI or mild dementia (n = 50) to generate a second Training Cohort that was matched on age, APOE genotype, clinical diagnosis, MMSE and Aβ-positivity to the Butler MAP Test Cohort (Table 2). This evidence concerns the gene APOE and dementia.