Analysis of DB7 BCBM tumor lysates using a murine bio-plex cytokine panel showed that rHSVQ treatment induced secretion of chemokines attracting Ly6G + neutrophils/PMN-MDSCs, such as CXCL1, GM-CSF, IL-6, IL-10 and MCP1 (Figure 6C and Supplementary Table S4), which was significantly reduced by oHSV-D11mt treatment. The gene discussed is CXCL1; the disease is neoplasm.