Above the degree of targets, the 14 key target points of the highest value were AKT1, MAPK3, IL6, TP53, VEGFA, TNF, SRC, MAPK1, STAT3, EGFR, CXCL8, JUN, CASP3, and MAPK8, suggesting that these 14 targets may be critical in AD with BSYJF treatment. Here, MAPK1 is linked to Alzheimer disease.