The most valuable target genes were AKT1, MAPK3, IL6, TP53, VEGFA, TNF, SRC, MAPK1, STAT3, EGFR, CXCL8, JUN, CASP3, and MAPK8, suggesting that these 14 targets may be the key of AD with BSYJF treatment. The gene discussed is MAPK3; the disease is Alzheimer disease.