GO enrichment analysis revealed that BP was mainly enriched in tube morphogenesis and vasculature development, etc. CC was mainly enriched in focal adhesion, etc. MF was mainly enriched in cell adhesion molecule binding, etc. KEGG analysis was primarily related to Pathways in cancer and PI3K-Akt signaling pathway, etc. The PI3K/Akt/mTOR signaling pathway is a crucial component in the process of colorectal carcinogenesis, playing significant roles not only in the development of drug resistance but also in the initiation of metastasis in colorectal cancer [19]. This evidence concerns the gene AKT1 and colorectal cancer.