In genetic terms, the causality found may be due to alterations in Human Leukocyte Antigen (HLA), CD40, and PINK1/Parkin genes in patients with MS and PD, which modulate the body’s immune-inflammatory response and mitochondrial autophagy, thereby influencing the occurrence of myocardial infarction [70–73]. This evidence concerns the gene PRKN and myocardial infarction.