Our main analysis according to CONUT scores showed that those will overall malnutrition (n = 2009) had significantly higher levels of CRP versus those with normal nutritional status (n = 454) (k = 4; MD: 0.40, 95% CI 0.08–0.72, I2 = 88%, P = 0.01) (Figure 7). This evidence concerns the gene CRP and nutritional deficiency disease.