Adjusting for age, sex, BMI, diabetes duration, HbA1c, insulin use, sBP, total cholesterol:HDL ratio (TC:HDL), statin use, smoking status and eGFR in the type 2 diabetes group alone, logPP was an independent predictor of the macrovascular endpoint (OR 1.021 (1.006–1.037), p = 0.0068, see Table 4). The gene discussed is INS; the disease is type 2 diabetes mellitus.