THY1 and thromboangiitis obliterans: Overexpression of the miR-144-3p mimic significantly upregulated the secretion of inflammatory cytokines and HA in Thy-1<sup>+</sup> OFs while inhibiting their proliferation.<h4>Conclusion</h4>Pla-Exos derived from patients with active TAO were immune-active, which may be a long-term stimulus casual for inflammatory and fibrotic progression of TAO.