This study aims to compare the predictive value of Quick Sequential Organ Failure Assessment (qSOFA), Systemic Inflammatory Response Syndrome (SISR), National Early Warning Score (NEWS), interleukin-6 (IL-6), and procalcitonin (PCT) for septicemia.<h4>Methods</h4>Patients who underwent percutaneous nephrolithotomy were included in the study and divided into a control group and a septic shock group. The gene discussed is IL6; the disease is Sepsis.