In humans, DLG1 was identified as a susceptibility gene for congenital anomalies of the kidney and urinary tract (CAKUT) (Westland et al, 2015), and a missense variant in DLG1 (p.T489R) was indeed identified in a patient with CAKUT (Nicolaou et al, 2016). Here, DLG1 is linked to congenital anomaly of kidney and urinary tract.