In the heterozygous gene model of IL-8-rs4073 study, the P-values for Asian, European and global effects were 0.329, 0.285 and 0.149, respectively, which were all greater than 0.05, indicating that IL-8-rs4073 gene polymorphism was not associated with neonatal sepsis under the heterozygous gene model. Here, CXCL8 is linked to Neonatal sepsis.