In the dominant gene model of IL-6-174G/C study, the P-values for non-conforming HWE, conforming HWE and the overall effects were 0.852, 0.835 and 0.950, respectively, which were all greater than 0.05, indicating that IL-6-174G/C gene polymorphism was not correlated with neonatal sepsis in the dominant gene model. This evidence concerns the gene IL6 and Neonatal sepsis.