Susanna Esposito et al. [33] suggested that the rs4073(IL-8 gene) genotype AT is associated with a significantly increased risk of severe sepsis, and Zhao Xiaofen et al. [44] suggested that the TT genotype at the rs4073 locus of IL-8 might be associated with susceptibility to sepsis in full-term newborns. This evidence concerns the gene CXCL8 and Sepsis.