Likewise, in the homozygous gene model of IL-8-rs4073 study, the P-values for Asian, European and global effects were 0.643, 0.178 and 0.187, respectively, which were all greater than 0.05,suggesting that IL-8-rs4073 gene polymorphism was not associated with neonatal sepsis in the homozygous gene model. This evidence concerns the gene CXCL8 and Neonatal sepsis.