Also, in the dominant gene model of TNF-α-308G/A (rs1800629) study, the P-values for Asian, European and global effects were 0.245, 0.658 and 0.872, respectively, which were all greater than 0.05, indicating that there was no correlation between TNF-α-308G/A (rs1800629) gene polymorphism and neonatal sepsis in the dominant gene model. The gene discussed is TNF; the disease is Neonatal sepsis.