Similar risk estimates were obtained using MR-Egger (OR = 0.864, 95% CI = 0.753–0.991, P = 0.039), weighted median (OR = 0.844, 95% CI = 0.752–0.947, P = 0.004), and weighted mode estimate (OR = 0.832, 95% CI = 0.734–0.943, P = 0.005) analyses, all of which were statistically significant, indicating that SHBG levels were associated with female infertility (Table 2). Here, SHBG is linked to female infertility.