In glioblastoma, the role of METTL3 in regulating mitophagy,6 tumor maintenance, and drug resistance7,8 via RNA m6A methylation9 has been shown, and one study described a role for METT7B in glioblastoma progression, potentially via the regulation of EGR1.10 The gene discussed is EGR1; the disease is glioblastoma.