These candidate variables included sex (p = 0.024, HR = 0.6, 95% CI: 0.38 to 0.95), Enneking stage (p = 0.006, HR = 3.2, 95% CI: 1.18 to 8.83), response to NAC (good or poor, p < 0.001, HR = 0.38, 95% CI: 0.23 to 0.62), tumour diameter (≥ or < 8 cm, p < 0.001, HR = 2.81, 95% CI: 1.87 to 4.24) and decline of Hb (p = 0.032, HR = 0.53, 95% CI: 0.28 to 0.99). This evidence concerns the gene GSTM1 and neoplasm.