MARS1 and influenza: In the cases of H. sapiens pancreatic glucokinase and influenza neuraminidase, we used knownactives and decoy compounds (presumed inactives) cataloged in theDUD-E database.25 In the case of T. brucei methionyl-tRNA synthetase, we used a compoundlibrary of known active and inactive compounds identified via PubChem.26