Of the total pathways, only nine conserved immune-related pathways, including the phosphoinositide 3-kinases (PI3K)-Akt signalling pathway, IL-17 signalling pathway, viral protein interaction with cytokines and cytokine receptors, primary immunodeficiency, T cell receptor signalling pathway, viral carcinogenesis, complement and coagulation cascades, TGF-β signalling pathway, and cytokine-cytokine receptor interaction, were significantly (p < 0.05) enriched at 1 dpi (Table 2). The gene discussed is AKT1; the disease is inborn error of immunity.