In addition, it has been found that short-course hypofractionated radiotherapy can effectively inhibit tumor growth and recruit T lymphocytes in draining lymph nodes, maintain low levels of suppressor T cells and high levels of effector T cells, and at the same time, short-course hypofractionated radiotherapy can increase the levels of IL-8, IL-6, TNFa and other factors, and has a stronger effect of promoting dendritic cell (DC) maturation and activation, thereby increasing the efficacy of immunotherapy (48, 49). The gene discussed is IL6; the disease is neoplasm.