GABRA1 and legionellosis: Conversely, it showed a negative association with complement and coagulation cascades, legionellosis, malaria, NF-kappa B signaling pathway, and pertussis (Figures 4A, B). Additionally, GABRA1 demonstrated associations with alanine, aspartate and glutamate metabolism, glycosaminoglycan biosynthesis, and GABAergic synapse (Figures 4C, D).