Conversely, it showed a negative association with complement and coagulation cascades, legionellosis, malaria, NF-kappa B signaling pathway, and pertussis (Figures 4A, B). Additionally, GABRA1 demonstrated associations with alanine, aspartate and glutamate metabolism, glycosaminoglycan biosynthesis, and GABAergic synapse (Figures 4C, D). This evidence concerns the gene GABRA1 and malaria.