Since AD is chiefly mediated by the proinflammatory SRTFs, encompassing NF‐ĸB and pSTAT3, as depicted in Figure 4, as well as AP1 (cFos and cJun), STAT1, and NFATs,3 the NTCI controls all of them thereby offering a new and unique treatment strategy for AD and other inflammatory skin diseases. Here, JUN is linked to inflammatory skin disease.