In addition, in a study on pregnant women with familial hyperaldosteronism type I, a condition that occurs due to an unequal crossover of the genes encoding steroid 11ß-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2), resulting in a chimeric CYP11B1/CYP11B2 gene with aldosterone synthase activity regulated by plasmatic adrenocorticotropes, we observed an improvement in BP concomitant with the normalization of aldosterone and ARR during pregnancy. Here, CYP11B1 is linked to glucocorticoid-remediable aldosteronism.