CYP11B2 and glucocorticoid-remediable aldosteronism: In addition, in a study on pregnant women with familial hyperaldosteronism type I, a condition that occurs due to an unequal crossover of the genes encoding steroid 11ß-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2), resulting in a chimeric CYP11B1/CYP11B2 gene with aldosterone synthase activity regulated by plasmatic adrenocorticotropes, we observed an improvement in BP concomitant with the normalization of aldosterone and ARR during pregnancy.