A 24-week regular Baduanjin exercise training could improve the physical frailty and cognitive function of the community-dwelling older adults with CF, seems to modulate oxidative stress and inflammatory processes by a reducing in circulating pro-oxidative MDA and 8-iso-PGF2α levels and an increasing of anti-oxidative SOD levels, as well as impacting inflammatory cytokines IFN-r, IL-2 and IL-4 levels. The gene discussed is IL4; the disease is cystic fibrosis.