TUG1 and central nervous system cancer: One study identified 630 genes as Tug1 targets using a modified RNA pull-down assay with promoter microarray analysis in BrU-labelled Tug1-transfected glioma cells.36 Cross-comparison of these 630 targets of Tug1 combined with 33 experimentally verified Tug1 targets against the list of differentially expressed genes in the heart, cerebellum and DRG of FRDAkd mice led to the identification of 40 overlapping genes (Fig. 3A).