Furthermore, an ROC analysis was done to assess the utility of these biomarkers in the diagnosis of RA.<h4>Results</h4>With the exception of leptin, adiponectin, and ADMA, there was a significant increase in the levels of PSGL-1, fibrinogen, AT-III, hsCRP, and lp(a) when compared to healthy controls. This evidence concerns the gene SERPINC1 and rheumatoid arthritis.