ART4 and autoimmune thrombocytopenic purpura: The pathophysiology of ITP, which is a destructive platelet disorder, is primarily IgG autoantibodies that attach to platelets and megakaryocytes [5], specifically targeting common surface antigens, including glycoprotein (GP) αIIbβ3 (GPIIbIIIA) and GPIb-IX-V [6].