WEE1 and autosomal dominant polycystic kidney disease: Whether interactions with any or all of these targets and signalling pathways in addition to the microtubule network is essential for the activity of mebendazole in ADPKD requires further experimental validation, however a synergistic effect of mebendazole on tubulin and protein kinases has been hypothesised to underlie its potent anticancer activity (Nygren et al., 2013; Bai R.-Y.