PKD2 and autosomal dominant polycystic kidney disease: A member of the wider group of ciliopathic disorders, autosomal dominant polycystic kidney disease (ADPKD) is caused primarily by mutations in the PKD1 or PKD2 genes, encoding the ciliary proteins polycystin 1 (PC1) and polycystin 2 (PC2), respectively (Bergmann et al., 2018).