In mouse xenograft MOLM‐16 tumors, a single intravenous dose of SD‐36 of 25 mg/kg resulted in a significant (>80%, 1 h and >95%, 6 h) and long‐lasting degradation (STAT3 levels below 50% for 4 days after a single administration) of STAT3 protein, culminating in complete tumor regression.173. Here, STAT3 is linked to neoplasm.