According to the recently published study, the majority of tumors initially designated as anaplastic gangliogliomas resolved into other CNS WHO diagnoses, most commonly pleomorphic xanthoastrocytoma, GB, IDH wild-type and diffuse pediatric-type high-grade glioma by the histological review, DNA methylation profiling, and NGS.7 Therefore, he was disease-free only for 7 months after standard treatment including craniotomy, adjuvant CCRT, and temozolomide. This evidence concerns the gene IDH1 and pleomorphic xanthoastrocytoma.