It ranges from 2% to 12%.8 According to the published studies for analysis of 4853 tumors by NGS, FGFR aberrations commonly affected 89% of gliomas.9 For infiltrative GB, 14 patients (3.6%) with FGFR mutant tumors were identified in another study.10 Among them, FGFR3-TACC3 fusion and FGFR3 amplification are the most common (64.3%). The gene discussed is FGFR3; the disease is central nervous system cancer.