BDNF and Stroke: The BDNF val66Met single nucleotide polymorphism (SNP) leads to intracellular packaging of proBNDF and secretion of mature BDNF (Chen et al., 2004; Yoshida et al., 2012) and is considered a key predictor of cognitive outcome and functional recovery after stroke in hospitalized patients (Rezaei et al., 2016; Han Z. et al., 2020).