The other pathway involves the production of fatty acid cholesterol esters by sterol O-acyltransferase 1 (SOAT1) in solute carrier family 47 member 1 (SLC47A1, also known as MATE1)-deficient human pancreatic ductal adenocarcinoma (PDAC) cells and NALM-6 leukemia cells, enhancing ferroptosis sensitivity [37]. This evidence concerns the gene SOAT1 and pancreatic ductal adenocarcinoma.