Moreover, F-box and WD repeat domain containing 7 (FBW7) inhibits SCD expression through the suppression of nuclear receptor 4 subfamily A group 1 (NR4A1), concurrently regulating apoptosis and ferroptosis in human pancreatic cancer cells (PANC1 and SW1990) [423]. This evidence concerns the gene FBXW7 and pancreatic neoplasm.